NFL Week 2 injury roundup
Michael Hickey / Getty Images Sport / Getty

Week 2 was not kind to a large number of NFL stars.

The incredible rash of injuries was headlined by New York Giants running back Saquon Barkley and San Francisco 49ers pass-rusher Nick Bosa, who both suffered knee injuries. Christian McCaffrey also exited late in the Carolina Panthers' loss to the Tampa Bay Buccaneers and did not return.

At least a few of the injuries appeared serious, as the Giants fear Barkley suffered a torn ACL and the 49ers fear Bosa has the same injury.

The 49ers were hit harder than others on Sunday. In addition to Bosa, three players exited early into their Week 2 contest, including quarterback Jimmy Garoppolo and starting running back Raheem Mostert.

Here's a list of key players who were either ruled out early or were unable to re-enter after being listed as questionable.

Player Team Injury
Saquon Barkley Giants Knee
Nick Bosa 49ers Knee
Jimmy Garoppolo 49ers Ankle
Raheem Mostert 49ers Knee
Solomon Thomas 49ers Knee
Christian McCaffrey Panthers Ankle
Davante Adams Packers Hamstring
Drew Lock Broncos Shoulder
Courtland Sutton Broncos Knee/Cramping
Cam Akers Rams Ribs
Joe Noteboom Rams Calf
Malik Hooker Colts Achilles
Parris Campbell Colts Knee
Byron Jones Dolphins Groin
Anthony Barr Vikings Shoulder
Mike Boone Vikings Concussion
Sterling Shepard Giants Toe
Kaleb McGary Falcons Knee
Ricardo Allen Falcons Elbow
Takk McKinley Falcons Groin
Foye Oluokun Falcons Hamstring
Breshad Perriman Jets Ankle
Quincy Wilson Jets Concussion
Dawson Knox Bills Concussion
Isaac Seumalo Eagles Knee
Brandon Scherff Washington Knee

The staggering numbers even caught the eye of other NFL players who weren't playing Sunday afternoon.

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NFL Week 2 injury roundup
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