Freiermuth was injured in the Nittany Lions' 38-25 loss to Ohio State on Oct. 31. The tight end's injury hasn't been specified by the team.
"The injury has prevented from playing at a high level and without pain, which led to the decision of surgery that his family and we made this week," said Franklin, according to Jon Sauber of Centre Daily Times. "He’s going to remain with the team for the rest of the season."
The junior is Penn State's all-time leader in touchdown receptions by a tight end with 16.
Freiermuth racked up 43 catches for 507 yards and seven touchdowns in 2019.
He's recorded 23 receptions for 310 yards and a touchdown in four games this season. Penn State will lean on Brenton Strange going forward.
Freiermuth, a potential first-round selection in the 2021 NFL Draft, joins linebacker Micah Parsons and running backs Journey Brown and Noah Cain as notable Penn State players expected to miss most of the season.
The Merrimac, Massachusetts native finishes his career in Happy Valley with 1,185 career receiving yards along with 16 touchdowns on 92 career receptions.